BIOLACT OVULES

Vaginal suppositories with probiotics for the treatment of vaginitis & the restoration of normal balance

10 vaginal pessaries

Bacillus Coagulans

Probiotics

Lactic Acid

pH Regulator

Chamomilla Recutita

Soothing action

Glucogen

Prebiotic

Why is this product suitable;

EVA INTIMA® BIOLACT OVULES is a medical device designed for the effective and safe restoration of the normal acidity of the vagina, when it is disturbed for reasons such as:
a) pathological conditions such as vaginal infections of bacterial or fungal etiology [vaginitis]
b) taking some medications such as antibiotics
c) normal conditions such as menstruation.
Thanks to the supply of live lactic bacteria in the form of the seed, the viability of the probiotic strains and their successful implantation in the vaginal mucosa is ensured, with the aim of the immediate remodeling of the beneficial flora.
Its composition is enriched with glycogen and lactic acid to ensure ideal conditions for the growth of lactic bacteria even under inflammatory conditions as well as with chamomile extract for immediate relief of itching, burning and irritation.
In a blister packaging for hygienic protection and ensuring the survival of the total population of lactic bacteria offered until the last dose.

Reshaping & maintaining acid balance

Innovative form of probiotics

Symbiotic product

1x 109 seeds of Bacillus coagulans per dose

How does it work?

The spores of lactic acid bacteria Bacillus coagulans are introduced into the vagina. At this point they are stimulated by the environmental conditions (lactic acid) & germinate taking their active form. They adhere to the empty points of the vaginal mucosa and begin to consume the existing food (glycogen) and release lactic acid. At the same time, multiplication begins and gradually the vaginal balance is reshaped.
It does not contain pharmaceutical substances, preservatives, synthetic colors and fragrances.

THERAPEUTIC:
A) Vaginitis after medication. One vaginal suppository per day for 4-8 days after the end of medication.
B) Atypical vaginitis without medication. One vaginal suppository per day for 6 to 8 days.

PREVENTIVE:
One vaginal suppository per week and one application for 2 days after the end of menstruation for those who maintain menstrual cycle.

Remove a vaginal suppository with its case from the blister, tearing at the perforated area. Open the case and remove the vaginal suppository by pulling the two flaps located at the bottom of the case in opposite directions. Insert the vaginal suppository deep into the vagina with the help of your index finger.

Important information:
The color of the suppository may vary from an off-white shade to darker beige with or without spot colorations. This phenomenon is normal and is not related to any alteration of the product.
Store in a shady place at a temperature not exceeding 25°C, away from children.
During the hot summer months, store in the refrigerator to avoid possible melting of the suppositories.

A recent study conducted by the Obstetric & Gynecological Clinic of Aretaieio Hospital and published in Beneficial Microbes with the title “Alleviation of vulvovaginitis symptoms: can probiotics lead the treatment plan?”, proved that the intravaginal administration of lactic acid bacteria Bacillus coagulans offered by Eva Intima Biolact before the administration of antimicrobial treatment, significantly reduces the four basic symptoms that women with vulvovaginitis experience such as itching, the sensation of burning, irritation and vaginal excessive secretions with simultaneous significant improvement and in the vaginal pH value within just 4 days.

Important is the benefit that results for the patient, for the period between the first visit until the completion of the diagnostic procedures, based on which the appropriate antimicrobial treatment will be administered.

More specifically, the clinical study includes 70 women of reproductive age with symptoms of vaginal discomfort, which are recorded during the first visit in special questionnaires.

At the same time, measurement of vaginal pH is performed and samples are taken through vaginal swabs for microscopic examination and culture. For the next 4 days, patients receive vaginal washes and vaginal suppositories with B. coagulans (Eva Biolact), with the appropriate antimicrobial treatment (based on the results of the diagnostic examination), being added after the fourth day of treatment.

Patients return to the Clinic after 16 days to complete the questionnaire again. The evaluation of the differences in the intensity of clinical signs of vaginitis as well as the measurement of vaginal pH between follow-up visits was performed based on the Wilcoxon signed-ranked test.

  • 91% of patients showed a significant reduction in the occurrence of burning sensation (p<0.001)
  • 85% of patients showed a significant reduction in the occurrence of itching (p<0.001)
  • 76% of patients showed a significant reduction in the occurrence of irritation (p<0.001)
  • 75% of patients showed a significant reduction in vaginal pH (p<0.001)
  • 71% of patients showed a significant reduction in the occurrence of vaginal discharge (p<0.001)

With the administration of the appropriate antimicrobial agent, the application of Eva Biolact ovule continued for 10 more days with the above clinical signs improving further based on the evaluation carried out during the patient’s third and final visit to the Clinic (graph).

However, the clinical improvement of symptoms is more significant during the period of treatment with probiotics only compared to the period of administration of the combination of antimicrobial treatment/probiotic.

In conclusion,
it is known that the reduction in the number of lactobacilli in the vaginal area is likely to lead to the appearance of minor or major disorders with the occurrence of simple vaginitis to complications in pregnancy and premature birth. The adoption of administering lactic acid bacteria in the first days of treatment offers:

  • Immediate symptom relief in a natural way – Immediate patient satisfaction
  • Provision of time margin for proper diagnostic examination and administration of appropriate therapeutic treatment
  • Immediate initiation of restoration of the physiology of the area and enhancement of defensive mechanisms
  • Contribution to the therapeutic outcome
  • Therapeutic success

We are here to answer you.

Every question corresponds to a need. For this reason it is worth answering it.

What is vaginitis?

Vaginitis is characterized as inflammation of the vaginal mucosa, that is, the membrane that covers the inner surface of the vagina.

The main symptoms of vaginitis regardless of its cause are the presence of itching, irritation, burning and excessive discharge of different texture, odor and color from the normal ones. Often there can be pain during sexual contact and urination.

The most common causes of vaginitis are bacteria and fungi while it can often be caused by the lack of estrogen or by allergy (for example from the use of condoms or other vaginal products). However, cases are not rare where there may be signs of inflammation without finding any specific cause. These cases are characterized as non-specific vaginitis and are usually attributed to hormonal imbalance (frequent during pregnancy).

Bacterial vaginitis is the most frequently occurring vaginitis. The symptoms that usually predominate are itching, irritation, burning and the appearance of excessive thin discharge with a strong fishy odor that can intensify after sexual contact or menstruation, grayish in color.

However, particular attention is required as there are sexually transmitted diseases caused by bacteria such as vaginal infection from trichomoniasis.

In any case, proper and safe diagnosis and treatment is achieved only through a gynecologist following a series of diagnostic tests (colposcopy, vaginal fluid culture, etc.), a practice that is recommended to follow every time you notice changes in the broader area.

Vaginitis caused by fungi is the second most frequently occurring vaginitis. It is not a sexually transmitted disease and it does not “spread” as fungi are part of the natural vaginal flora, where they naturally remain in low populations. Common causes of their overgrowth that can lead to the manifestation of vaginitis are situations that lead to a reduction of lactobacilli in the vagina and the predominance of other microorganisms in the area (e.g. after taking antibiotics for any reason, use of inappropriate and strong antiseptic vaginal solutions, etc.).

The symptoms that most commonly occur include intense itching, irritation, a burning sensation, and excessive vaginal discharge that is thick in consistency and white in color, commonly referred to as leukorrhea, without the presence of any characteristic unpleasant odor.

In any case, proper and safe diagnosis and treatment is achieved only through a gynecologist following a series of diagnostic tests (colposcopy, vaginal fluid culture, etc.), a practice that is recommended to follow every time you notice changes in the broader area.

Depending on the symptoms that concern you there are product options that can relieve you. However, complete relief from the cause of inflammation cannot be achieved unless diagnosis has been made and appropriate treatment has been given by your gynecologist.

In case of bacterial etiology vaginitis you can combine (diagram for bacterial vaginitis)
In case of fungal etiology vaginitis you can combine (diagram for fungal vaginitis)
In case of non-specific etiology vaginitis you can combine (diagram for atypical vaginitis)

The appearance of vaginitis can be prevented if the natural flora of the area is maintained with the predominance of lactobacilli, the acidic environment of the vagina (pH 3.5-4.5) with the presence of lactic acid and the necessary moisture for the tissues. The assurance of these factors prevents the development of infections. In case these are disrupted, appropriate product options such as probiotics, vaginal pH regulators and hydration products can help restore and maintain these and prevent the appearance of infections.

PREVENTION OF VAGINITIS AFTER MENSTRUATION

Tips:

  • You can adopt daily intake of probiotics by mouth through special supplements with lactobacilli so that you easily and naturally strengthen the flora of the vagina to use daily special cleansing liquids for the sensitive area with enhanced composition regarding protection from microorganisms.

The transition to reproductive age is marked by the periodic appearance of bleeding that lasts for a few days and usually occurs every 24 to 28 days. The presence of blood in the vaginal area – although physiological – can lead to minor disturbances in the vaginal environment affecting vaginal pH and the presence of lactobacilli as blood carries a neutral pH value. This effect combined with the fact that blood is a favorable nutritional substrate for fungi that naturally exist in the vagina, often lead to the organism’s inability to control fungal overgrowth which ultimately causes inflammation in the area.
Strengthening the natural mechanism of removing blood residues and the immediate restoration of vaginal pH to its natural acidic values can limit the appearance of vaginitis after the end of the period.

Indicatively you can combine (diagram for prevention of vaginitis and strengthening of natural balance after the period)

Tips:

  • Prefer the use of sanitary pads with cotton covering which you change regularly compared to tampons
  • to use daily special cleansing liquids for the sensitive area with enhanced composition regarding protection from microorganisms.

You can adopt daily intake of probiotics by mouth through special supplements with lactobacilli so that you easily and naturally strengthen the flora of the vagina

Although fungi are natural inhabitants of the vagina they very often lead to infections while there are specific reasons that reduce the probability of successful control of these and relief from the manifestations of vaginitis. As a result, reappearance of symptoms of fungal vaginitis is often recorded very soon after the previous episode of it, a fact that is characterized as recurrence. Main causes are the development of resistance to common drug treatments, inadequate diagnosis, self-diagnosis, non-compliance with treatment regimens, etc.
In any case, proper and safe diagnosis and treatment is achieved only through a gynecologist following a series of diagnostic tests (colposcopy, vaginal fluid culture, identification of responsible strains, selection of effective active agents each time, etc.), a practice that is recommended to follow every time you notice changes in the broader area.
Careful adherence to treatment regimens and the adoption of practices that directly strengthen the local balance and defense of the area are the means for successful prevention of recurrences.

PREVENTION OF VAGINITIS AFTER MENSTRUATION

Tips:

  • to choose cotton underwear and to limit the use of tight synthetic underwear
  • to avoid the use of daily sanitary pads
  • to change swimwear immediately and not to sit directly on beach sand
  • to avoid tight clothing in general and anything that can significantly increase the humidity and temperature of the area
  • to use daily special cleansing liquids for the sensitive area with enhanced composition regarding protection from fungi.

Probiotics are living microorganisms which do not cause disease in the human body and contribute in many ways to ensuring its health such as preventing the development of other pathogenic microorganisms, contributing to the digestion of food, etc.

Naturally, in most cavities of the human body such as the skin, there is flora meaning microorganisms that over the years have managed to coexist harmoniously with humans and develop with them a mutually reciprocal relationship (microorganisms find fertile ground to survive and at the same time strengthen the first line of defense of the human body). In case there is a disruption of the natural flora such as from taking antibiotics then pathogenic microorganisms are easily given the opportunity to develop and cause infections. The sooner the restoration of the natural flora with the use of probiotic preparations the more it contributes to the effective control of pathogenic microorganisms and the prevention of development of new ones.

The natural flora that can colonize different cavities of the body differs significantly from place to place, depending on the age of the person, their dietary habits, their lifestyle, etc. For the vaginal cavity the microorganisms that have predominated over the years and contribute significantly to maintaining the balance of the area are lactobacilli. This type of bacteria needs to dominate each time especially during the reproductive age of women so that the acidic environment in the area is maintained. In case the population of lactobacilli is disrupted the probability of the appearance of pathological conditions increases. Probiotic preparations that act effectively restoring and restoring vaginal flora are those that carry in their composition a large amount of lactobacilli – the type of bacteria that naturally predominate in the vagina and shape the desired acidic environment and pH of vaginal fluid.

There are bacterial strains that are used as probiotics which by their nature have the ability depending on the conditions that prevail to take two forms:
– the spore form, a resistant form that protects the microorganism when environmental conditions threaten its viability,
– the vegetative form, which gives the microorganism the ability to develop and multiply when conditions are favorable.
The choice of probiotic preparations that offer their bacterial strains in spore form ensures that the microorganism reaches the desired target tissue alive despite all the processing it has undergone during the stages of production, packaging, storage and transport. Thus the maximum effectiveness of their use is achieved.

Since eva intima biolact ovules contains populations of living lactobacilli in spore form, there may be slight variations in the color of the suppository (from off-white to light gray-beige), a fact that is considered normal as it depends on the culture media that were used each time for the development of these bacteria.

The application of vaginal suppositories is beneficial whenever you choose to perform it without any restriction on the frequency of use. However, when the issue of restoring flora after infections is raised at least 8 days are required so that a strong and intact population of lactobacilli is reformed in the area.

Lactic acid is the factor that shapes the acidic environment in the vagina.
During reproductive age it is released by the lactobacilli of the normal vaginal flora after metabolism of glycogen that they use as food. The acidic vaginal environment is favorable and enhances the action of lactobacilli while at the same time restricts the development of other pathogenic microorganisms. However, even beyond reproductive age such as during post-menopause, maintaining acidic conditions in the vagina can be a means for preventing the manifestation of infections. At this stage of a woman’s life, vaginal pH regulators that offer ready-made lactic acid and directly shape the required acidity in the vagina can help directly.

Itching, irritation and burning sensation are clinical manifestations that can be observed in conditions of different etiology in the vaginal area. They are usually observed in cases of infection of various etiologies where they coexist simultaneously with increased vaginal discharge with or without odor. The presence of these symptoms without the presence of excessive discharge can be due to the manifestation of vaginal dryness.

In any case, proper and safe diagnosis and treatment is achieved only through a gynecologist following a series of diagnostic tests (colposcopy, vaginal fluid culture, etc.), a practice that is recommended to follow every time you notice changes in the broader area.

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